OLUX-E^® Foam Efficacy - Plaque Psoriasis

OLUX-E^® Foam Effectively Clears Symptoms Overall With Proven Efficacy

Percent of Patients Clear or Almost Clear and Achieving Composite Endpoint of Treatment Success at Week 2^*2,3

* Data derived from a phase 3, double-blind, randomized studies (at Week 2). An Investigator's Static Global Assessment (ISGA) score of clear (0) or almost clear (1) was utilized, reflecting the traditional definition of treatment success; success rates were 47% vs 12% for Vehicle Foam in psoriasis patients (P<0.0001). The composite endpoints measuring treatment success required multiple criteria; success rates were 16% vs 4% for Vehicle Foam in psoriasis patients (P=0.0005).

OLUX-E^® Foam Effectively Treats Mild to Moderate Plaque-Type Psoriasis.

Percent of Patients (n=253) Clear or Almost Clear of Plaque Psoriasis Symptoms at Week 2^*2

* Results from a phase 3, double-blind, randomized study, which measured the proportion of patients using OLUX-E^® Foam vs Vehicle Foam who had a score of 0 or 1 for scaling (71% vs 28%; P<0.0001), a score of 0 or 1 for erythema (53% vs 20%; P<0.0001), a score of 0 (42% vs 19%; P<0.0001) for pruritus, and a score of 0 for plaque thickness (31% vs 5%; P<0.0001) at Week 2. Endpoints required a minimum 2-grade improvement.

Phase 3 Study

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